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Doxefazepam



Doxefazepam
Systematic (IUPAC) name
9-chloro-6-(2-fluorophenyl)-4-hydroxy
-2-(2-hydroxyethyl)-2,5-diazabicyclo
[5.4.0]undeca-5,8,10,12-tetraen-3-one
Identifiers
CAS number 40762-15-0
ATC code N05CD12
PubChem 38668
DrugBank ?
Chemical data
Formula C17H14ClFN2O3 
Mol. mass 348.8
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule IV(US)

Routes Oral

Doxefazepam (marketed under brand name Doxans) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic in laboratory animals.[1]

Additional recommended knowledge

Doxefazepam is not approved for sale in the United States or Canada.

References

  1. ^ Babbini, M.; Torrielli MV, Strumia E, Gaiardi M, Bartoletti M, De Marchi F. (August 1975). "Sedative-hypnotic properties of a new benzodiazepine in comparison with flurazepam. Pharmacological and clinical findings". Arzneimittel-Forschung 25 (8): 1294-1300. PubMed.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Doxefazepam". A list of authors is available in Wikipedia.
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