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Bromisoval



Bromisoval
Systematic (IUPAC) name
2-bromo-N-carbamoyl-3-methylbutanamide
Identifiers
CAS number 496-67-3
ATC code N05CM03
PubChem 2447
Chemical data
Formula C6H11BrN2O2 
Mol. mass 223.068 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes Oral

Bromisoval (INN; commonly known as bromvalerylurea) is a hypnotic and sedative. It is marketed over the counter in Asia under various trade names, usually in combination with non-steroidal anti-inflammatory drugs.

Additional recommended knowledge

Chronic use of bromisoval has been associated with bromine poisoning.[1][2][3]

References

  1. ^ Hashida H, Honda T, Morimoto H, Aibara Y (2001). "[A case of chronic bromvalerylurea intoxication due to habitual use of commercially available nonsteroidal anti-inflammatory drugs presenting an indefinite hyperchloremia]" (in Japanese). Nippon Ronen Igakkai Zasshi (Japanese Journal of Geriatrics) 38 (5): 700–3. PMID 11605223.
  2. ^ Kawakami T, Takiyama Y, Yanaka I, et al (1998). "Chronic bromvalerylurea intoxication: dystonic posture and cerebellar ataxia due to nonsteroidal anti-inflammatory drug abuse". Intern Med 37 (9): 788–91. PMID 9804091.
  3. ^ Wang YT, Yang SY, Wu VC, Wu KD, Fang CC (2005). "Pseudohyperchloraemia due to bromvalerylurea abuse". Nephrol Dial Transplant 20 (8): 1767–8. doi:10.1093/ndt/gfh945. PMID 15972320. full text


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bromisoval". A list of authors is available in Wikipedia.
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