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Diproqualone



Diproqualone
Systematic (IUPAC) name
3-(2,3-dihydroxypropyl)-2-methyl-quinazolin-4-one
Identifiers
CAS number 36518-02-2
ATC code  ?
PubChem 64112
Chemical data
Formula C12H14N2O3 
Mol. mass 234.251
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Diproqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other european countries. It has sedative, anxiolytic, antihistamine and analgesic properties, and is used primarily for the treatment of inflammatory pain associated with osteoarthritis and rheumatoid arthritis[1], and more rarely for treating insomnia, anxiety and neuralgia. [2]

Additional recommended knowledge

Diproqualone is the only analogue of methaqualone that is still in widespread clinical use, due to its useful anti-inflammatory and analgesic effects in addition to the sedative and anxiolytic actions common to other drugs of this class. There are still some concerns about the potential of diproqualone for abuse and overdose, and so it is not sold as a pure drug but only as the camphosulfonate salt in combination mixtures with other medicines such as Ethenzamide.


See also

References

  1. ^ Audeval B, Bouchacourt P, Rondier J. Comparative study of diproqualone-ethenzamide versus glafenine for the treatment of rheumatic pain of gonarthrosis and coxarthrosis. (French) Gazette médicale de France 1988; 95(25):70-72
  2. ^ http://www.biam2.org/www/subMCCAMSILATE_DE_DIPROQUALONE.html
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diproqualone". A list of authors is available in Wikipedia.
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