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Halazepam



Halazepam
Systematic (IUPAC) name
9-chloro-6-phenyl-2-(2,2,2-trifluoroethyl)-2,5-diazabicyclo
[5.4.0]undeca-5,8,10,12-tetraen-3-one
Identifiers
CAS number 23092-17-3
ATC code N05BA13
PubChem 31640
DrugBank APRD01009
Chemical data
Formula C17H12ClF3N2O 
Mol. mass 352.7
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

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Legal status

Schedule IV (US)

Routes Oral

Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam.[1] While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them.[2]

Additional recommended knowledge

References

  1. ^ Greenblatt, D. J.; A. Locniskar and R. I. Shader (June 12, 1982). "Halazepam, another precursor of desmethyldiazepam". Lancet 1 (8285): 1358-9. PubMed.
  2. ^ Fann, W. E.; W. M. Pitts and J. C. Wheless (Mar-Apr 1982). "Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine". Pharmacotherapy 2 (2): 72-9. PubMed.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Halazepam". A list of authors is available in Wikipedia.
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