To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Etifoxine (or etafenoxine) is an anxiolytic and anticonvulsant drug. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It is more effective than lorazepam as an anxiolytic, but has less side effects.
Additional recommended knowledge
Unlike benzodiazepines, etifoxine appears to produce its anxiolytic effects by binding to β2 and β3 subunits of the GABAA receptor complex, and so is acting at a different target site to benzodiazepines, although the physiological effect that is produced is similar to that of benzodiazepines. This difference in binding means that etifoxine can be used alongside benzodiazepines to potentiate their effects without competing for binding sites, however it also means that the effects of etifoxine are not reversed by the benzodiazepine antagonist flumazenil.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Etifoxine". A list of authors is available in Wikipedia.|