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Systematic (IUPAC) name
(2R,3S)-3-(3,4-dichlorophenyl)-2-ethoxymethyl- 8-methyl-8-azabicyclo[3.2.1]octane
CAS number 402856-42-2
ATC code  ?
PubChem  ?
Chemical data
Formula C17H23Cl2NO 
Mol. mass 328.28 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes  ?

Tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor, which also seems to increase the action of acetylcholine in the brain, probably due to downstream effects. It was originally researched for the treatment of Alzheimer's disease and Parkinson's Disease, but was subsequently dropped from development for these applications, and is now being researched for the treatment of obesity, presumably as an appetite suppressant. As of 2006 it was in Phase II trials for the treatment of obesity.[1]


    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tesofensine". A list of authors is available in Wikipedia.
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