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Rupatadine



Rupatadine
Systematic (IUPAC) name
8-chloro-6,11-dihydro-11-(1-((5-methyl-3-pyridyl)methyl)-
4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Identifiers
CAS number 158876-82-5
ATC code R06AX28
PubChem 133017
Chemical data
Formula C26H26ClN3 
Mol. mass 415.958 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 99%
Metabolism Hepatic, CYP-mediated
Half life 5.9 hours
Excretion Fecal (60.9%) and renal (34.6%)
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

Rupatadine is a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. Ruptatadine is marketed by Panacea-Biotech under the trade name Ralif. Ralif is approved for the treatment of allergic rhinitis.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Rupatadine". A list of authors is available in Wikipedia.
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