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VMAT1



solute carrier family 18 (vesicular monoamine), member 1
Identifiers
Symbol SLC18A1
Alt. Symbols VMAT1, VAT1
Entrez 6570
HUGO 10934
OMIM 193002
RefSeq NM_003053
UniProt P54219
Other data
Locus Chr. 8 p21.3

For norepinephrine to be acted upon by PNMT in the cytosol, it must first be shipped out of granules of the chromaffin cells. This may occur via the catecholamine-H+ exchanger VMAT1.

VMAT1 is also responsible for transporting newly synthesized epinephrine from the cytosol back into chromaffin granules in preparation for release.


v • d • e
Membrane transport protein: neurotransmitter transporters
Glutamate - Monoamine (DAT, NET, SERT) - Vesicular monoamine (VMAT1, VMAT2) - Vesicular acetylcholine
v • d • e
Membrane proteins, carrier proteins: membrane transport proteins
ABC-transporterA1, A2, A4, A12, B1, B2-3, B4, B5, B11, C1, C2, C4, C5, C6, C8, C8-9, C11, D1, D3, E1, G1, G2, G5, G8
Solute carrier1A1-7, 1A1, 1A2, 1A3, 1A5, 2A1, 2A2, 2A3, 2A4, 3A1, 3A2, 4A1, 4A4, 4A7, 5A1-2, 5A5, 6A1, 6A2, 6A3, 6A8, 6A4, 7A5, 7A9, 8A1-3, 9A1, 9A3, 10A2, 11A1, 11A2, 11A3, 12A1-2, 12A3, 15A1, 17A5, 17A6-8, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 23A1, 23A2, 24A1-2, 24A5, 25A4-6, 25A8, 25A13, 25A15, 25A20, 26A2, 26A3, 26A4, 29A1, 29A2, 30A8, 31A1, 31A2, 34A1, 37A4, 39A4, 40A1, O1B1
MonosaccharideGLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT8
OtherAmino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Karyopherin)
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "VMAT1". A list of authors is available in Wikipedia.
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