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Vesicular monoamine transporter

The vesicular monoamine transporter is a transport protein located within the presynaptic cell. It comprises the two isoforms:

Substrates for the transporter is mainly noradrenaline, adrenaline and isoprenaline. However, other substrates include dopamine, 5-HT, guanethidine and MPP+.[1]

It can be inhibited by reserpine and tetrabenazine.[1]

Further reading

  • Kilbourn MR (1997). "In vivo radiotracers for vesicular neurotransmitter transporters". Nucl. Med. Biol. 24 (7): 615-9. PMID 9352531.
  • Weihe E, Eiden LE (2000). "Chemical neuroanatomy of the vesicular amine transporters". FASEB J. 14 (15): 2435-49. doi:10.1096/fj.00-0202rev. PMID 11099461.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Vesicular_monoamine_transporter". A list of authors is available in Wikipedia.
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