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Systematic (IUPAC) name
CAS number 7361-61-7
ATC code  ?
PubChem 5707
Chemical data
Formula C12H16N2S 
Mol. mass 220.33
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status

Veterinary Use

Routes  ?

Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other large mammals {non-human}. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. Yohimbine (Yobine) can be used to reverse xylazine effects. In veterinary anesthesia, xylazine is often used in combination with ketamine. No formal information in humans available. Xylazine is sold by Bayer under the brand name Rompun.


  • McCurnin, DM, and JM Bassert. Clinical Textbook for Veterinary Technicians, 5th ed. Saunders, Philadelphia, PA. 2002.
  • Bayer Healthcare - Rompun Homepage 2005.
  • Wright, Dr. Bob. Human Health Concerns When Working With Medications Around Horses. Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA). 2005.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Xylazine". A list of authors is available in Wikipedia.
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