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Nitisinone



Nitisinone
Systematic (IUPAC) name
2-[2-nitro-4-(trifluoromethyl)benzoyl]
cyclohexane-1,3-dione
Identifiers
CAS number 104206-65-7
ATC code A16AX04
PubChem 115355
DrugBank APRD01141
Chemical data
Formula C14H10F3NO5 
Mol. mass 329.228 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life Approximately 54 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nitisinone". A list of authors is available in Wikipedia.
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