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Systematic (IUPAC) name
Human Beta-glucocerebrosidase
CAS number 37228-64-1
ATC code A16AB01
PubChem  ?
DrugBank BTD00037
Chemical data
Formula C2532H3854N672O711S16 
Mol. mass 55597.4 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3.6–10.4 min
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Alglucerase is a modified form of human β-glucocerebrosidase where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is a citrate buffered solution of Alglucerase manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease although it has been largely replaced by Cerezyme® which is produced by Recombinant DNA technology.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Alglucerase". A list of authors is available in Wikipedia.
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