Oligonucleotide Synthesis

News Oligonucleotide Synthesis

• Proligo Licensed to Manufacture and Market Oligos Labeled with Beckman Coulter WellRED Dyes

  Boulder Oct. 15, 2002 - Proligo(R) and Beckman Coulter, Inc. announced today a worldwide supply and license agreement by which Proligo will manufacture and sell oligonucleotides labeled with Beckman Coulter WellRED Dyes, D2-PA, D3-PA, D4-PA. These new oligos will run on Beckman Coulter's CEQ(TM) more

Publications Oligonucleotide Synthesis

• Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes

  Abstract Double‐labeled oligonucleotide probes containing fluorophores interacting by energy‐transfer mechanisms are essential for modern bioanalysis, molecular diagnostics, and in vivo imaging techniques. Although bright xanthene and cyanine dyes are gaining increased prominence within these fi more

• Molecules, Vol. 17, Pages 12378-12392: Synthesis of a Cholesteryl-HEG Phosphoramidite Derivative and Its Application to Lipid-conjugates of the Anti-HIV 5'TGGGAG3' Hotoda’s Seq ...

  A novel phosphoramidite derivative of cholesterol, with an ether-linked hexaethylene glycol (HEG) spacer arm, has been obtained through simple and reproducible solid phase modified oligonucleotide synthesis manipulations. This building block and the known phosphoramidite derivative of 3b-(2-hydroxye more

• Molecules, Vol. 17, Pages 12102-12120: Acetylated and Methylated β-Cyclodextrins as Viable Soluble Supports for the Synthesis of Short 2′-Oligodeoxyribo-nucleotides in Solution

  Novel soluble supports for oligonucleotide synthesis 11a–c have been prepared by immobilizing a 5′-O-protected 3′-O-(hex-5-ynoyl)thymidine (6 or 7) to peracetylated or permethylated 6-deoxy-6-azido-β-cyclodextrins 10a or 10b by Cu(I)-promoted 1,3-dipolar cycloaddition. The app more

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