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Aldicarb is a carbamate insecticide with structural formula: 2-methyl-2-(methylthio)propionaldehyde O-methylcarbamoyloxime. Aldicarb is the active substance in Temik pesticide, which is effective against thrips, aphids, spider mites, lygus, fleahoppers, and leafminers but is primarily used as a nematicide. In mammals it is a cholinesterase inhibitor (prevents neurotransmitter breakdown). In case of severe poisoning, the victim dies of respiratory failure. It is also highly toxic for birds.
Additional recommended knowledge
Aldicarb is approved by the USEPA for use by professional pesticide applicators on a variety of crops, including cotton, beans, and others. It is not approved for household use.
"Tres Pasitos", a mouse, rat, and roach killer that contains high concentrations of aldicarb, has been illegally imported into the United States from Mexico and other Latin American countries. The product is highly toxic to animals and people, and it should not be used. EPA
Toxicity in mammals
Aldicarb is a fast-acting cholinesterase inhibitor, causing rapid accumulation of acetylcholine at the synaptic cleft. It is widely used to study cholinergic neurotransmission in simple systems such as the nematode C. elegans.
Exposure to high amounts of aldicarb can cause weakness, blurred vision, headache, nausea, tearing, sweating, and tremors in people. Very high doses can kill people, because it can paralyze the respiratory system. EPA
It has a LD50 rating of 0.5 - 1.5 mg/kg when in liquid form and a LD50 rating of 7mg/kg when in solid form.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Aldicarb". A list of authors is available in Wikipedia.|