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Low density lipoprotein receptor-related protein 8



Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Identifiers
Symbol LRP8; ApoER2
Entrez 7804
HUGO 6700
OMIM 602600
RefSeq NM_004631
UniProt Q14114
Other data
Locus Chr. 1 p32.3

Low density lipoprotein receptor-related protein 8, or LRP8 (also Apolipoprotein E Receptor 2; ApoER2) is a member of the LDL receptor family that plays a role in endocytosis and signal transduction. Together with VLDLR it is able to bind reelin, leading to the phosphorylation of DAB1, which binds on its cytosolic tail.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Low_density_lipoprotein_receptor-related_protein_8". A list of authors is available in Wikipedia.
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