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Aristolochic acid



Aristolochic acid
Other names Aristolochic acid I
  • Aristinic acid
  • Aristolochia yellow
  • Aristolochic acid A
  • Aristolochin
  • Aristolochine
  • Descresept
  • Isoaristolochic acid
  • Tardolyt
  • TR 1736

Aristolochic acid II

  • Aristolochic acid B
Identifiers
CAS number 313-67-7
Properties
Molecular formula C17H11NO7
Molar mass 341.27684 g/mol
Density  ? g/cm3
Melting point

260 - 265 °C

Boiling point

°C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Aristolochic acid is a rodent carcinogen found in the Aristolochia and Asarum species, both in the Aristolochiaceae family of plants. Aristolochic acid is composed of a ~1:1 mixture of two forms, aristolochic acid I and aristolochic acid II.

Additional recommended knowledge

In addition to its carcinogenicity, aristolochic acid is also highly nephrotoxic and may be a causative agent in Balkan nephropathy. However, despite these well-documented dangers, aristolochic acid is still sometimes used as a herbal remedy for weight loss.

References

  • FDA Warns Consumers to Discontinue Use of Botanical Products that Contain Aristolochic acid. April 11 2001. Website-http://www.cfsan.fda.gov/%20~dms/addsbot.html
  • FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid. April 2001. Website-http://www.cfsan.fda.gov/~dms/ds-bot.html
  • Health Canada advising not to use products labelled to contain Aristolochia. August 2001. Website - http://www.hc-sc.gc.ca/ahc-asc/media/advisories-avis/2001/2001_91_e.html
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Aristolochic_acid". A list of authors is available in Wikipedia.
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