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Benactyzine



Benactyzine
Systematic (IUPAC) name
2-diethylaminoethyl 2-hydroxy-2,2-di(phenyl)acetate
Identifiers
CAS number 302-40-9
ATC code  ?
PubChem 9330
Chemical data
Formula C20H25NO3 
Mol. mass 327.42 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Benactyzine is an anticholinergic drug. It is a glycolic acid ester, related to other drugs such as the piperidinyl benzilates and 3-Quinuclidinyl benzilate but with much less potent anticholinergic effects.

Additional recommended knowledge

Benactyzine has been used as an antidepressant,[1] however its use for this application is limited by anticholinergic side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects. Consequently it is no longer widely used in medicine, although it is still a useful drug for scientific research.




References

  1. ^ McLaughlin B, Rickels K, Abidi M, Toro R. Meprobamate-benactyzine (Deprol) and placebo in two depressed outpatient populations. Psychosomatics. 1969 Mar-Apr;10(2):73-81.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Benactyzine". A list of authors is available in Wikipedia.
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