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Bottom-up proteomics is a method for the identification of proteins in complex mixtures through a combination of two-dimensional gel electrophoresis and mass spectrometry. The name is derived from the analogous bottom-up DNA sequencing. Mass spectrometry analysis consists of a single stage of mass spectrometry for peptide mass fingerprinting or tandem mass spectrometry to obtain a peptide sequence tag.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bottom-up_proteomics". A list of authors is available in Wikipedia.|