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CCL1



chemokine (C-C motif) ligand 1
Identifiers
Symbol CCL1
Alt. Symbols SCYA1, I-309, TCA3, P500, SISe
Entrez 6346
HUGO 10609
OMIM 182281
PDB 1EL0
RefSeq NM_002981
UniProt P22362
Other data
Locus Chr. 17 q11.2

Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. [1] CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.[2] This chemokine resides in a large cluster of CC chemokines on human chromosome 17.

Additional recommended knowledge

References

  1. ^ Miller and Krangel. The Human Cytokine I-309 is a Monocyte Chemoattractant. Proceedings of the National Academy of Sciences, 1992, Vol 89, 2950-2954.
  2. ^ Roos et al., Identification of CCR8, the receptor for the human CC chemokine I-309. J Biol Chem 1997 Vol 272, 17251–4.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "CCL1". A list of authors is available in Wikipedia.
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