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Clebopride



Clebopride
Systematic (IUPAC) name
4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-
2-methoxybenzamide
Identifiers
CAS number 55905-53-8
ATC code A03FA06
PubChem 2780
Chemical data
Formula C20H24ClN3O2 
Mol. mass 373.876 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.

Additional recommended knowledge

A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.[1]

References

  1. ^ Cuena Boy R, Maciá Martínez MA (1998). "[Extrapyramidal toxicity caused by metoclopramide and clebopride: study of voluntary notifications of adverse effects to the Spanish Drug Surveillance System]" (in Spanish). Atencion Primaria 21 (5): 289–95. PMID 9608114. Free full text


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Clebopride". A list of authors is available in Wikipedia.
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