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Systematic (IUPAC) name
2-diethylaminoethyl1- cyclohexylcyclohexane- 1-carboxylate
CAS number 77-19-0
ATC code A03AA07
PubChem 3042
DrugBank APRD00113
Chemical data
Formula C19H35NO2 
Mol. mass 309.487 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding >99%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Dicyclomine is an anticholinergic that blocks muscarinic receptors. Dicyclomine is known as dicycloverine hydrochloride in the UK.

Clinical uses

Dicyclomine is used to treat intestinal hypermotility, the symptoms of Irritable Bowel Syndrome (IBS) (also known as spastic colon). It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body. It is a smooth muscle relaxer.

In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.

It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada.

Side effects

Dicyclomine can cause a range of anticholinergic side effects such as dry mouth, nausea and at higher doses, deliriant effects. Abuse of this drug has been reported in Brazil.[1]


  1. ^ Carlini EA. Preliminary note: dangerous use of anticholinergic drugs in Brazil. Drug and Alcohol Dependence. 1993 Mar;32(1):1-7.
  • Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
  • Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dicycloverine". A list of authors is available in Wikipedia.
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