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Compartment (pharmacokinetics)



In pharmacokinetics, a compartment is a defined volume of body fluids. It is distinguished from anatomic compartments, which are bounded by fasciae.

Additional recommended knowledge

Examples

There are five major body compartments[1]:

  • blood plasma
  • interstitial fluid
  • fat tissue
  • intracellular fluid
  • transcellular fluid

The transcellular compartment includes fluids in the pleural cavity or peritoneal cavity.

Comparison table

Compartment estimated % of body mass[2]
blood plasma 5
interstitial fluid 16
fat tissue 20
intracellular fluid 35
transcellular fluid 2

References

  1. ^ Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 102
  2. ^ Unless else specified in table, then ref s: Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 102
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Compartment_(pharmacokinetics)". A list of authors is available in Wikipedia.
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