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Crocin is a natural carotenoid chemical compound that is found in the flowers crocus and gardenia. It is the diester formed from the disaccharide gentiobiose and the dicarboxylic acid crocetin. It has a deep red color and forms crystals with a melting point of 186 °C. When dissolved in water, it forms an orange solution.

Crocin is the chemical ingredient primarily responsible for the color of saffron. It has also been shown to be a potent antioxidant. [1] [2] [3] It has also been shown to have an anticarcinogenic action. [4] [5] [6]


  1. ^ Papandreou MA, Kanakis CD, Polissiou MG, Efthimiopoulos S, Cordopatis P, Margarity M, Lamari FN. (2006). "Inhibitory activity on amyloid-beta aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents.". J Agric Food Chem. 54 (23): 8762–8. PMID 17090119.
  2. ^ Ochiai T et al. (2006). "Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.". Biochim Biophys Acta. 1770 (4): 578-584. PMID 17215084.
  3. ^ Zheng YQ, Liu JX, Wang JN, Xu L. (2006). "Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia.". Brain Res. 1138: 86-94. PMID 17274961.
  4. ^ Escribano J, Alonso GL, Coca-Prados M, Fernandez JA. (1996). "Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro.". Cancer Letters 100 (1-2): 22-30. PMID 8620447.
  5. ^ Chryssanthi DG, Lamari FN, Iatrou G, Pylara A, Karamanos NK, Cordopatis P. (2007). "Inhibition of breast cancer cell proliferation by style constituents of different Crocus species.". Anticancer Research 27 (1A): 357-62. PMID 17352254.
  6. ^ Abdullaev Jafarova F, Caballero-Ortega H, Riverón-Negrete L, Pereda-Miranda R, Rivera-Luna R, Manuel Hernández J, Pérez-López I, Espinosa-Aguirre JJ. (2002). "In vitro evaluation of the chemopreventive potential of saffron.". Rev. Invest. Clin. 54 (5): 430-6. PMID 12587418.

See also

  • Gardenia
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Crocin". A list of authors is available in Wikipedia.
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