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Dimercaptosuccinic acid, or DMSA, is the chemical compound with the formula HO2CCH(SH)CH(SH)CO2H. This colourless solid contains two carboxylic acid and two thiol groups, the latter being responsible for the mildly unpleasant odour of this dicarboxylic acid. It occurs in two diastereomeric forms, meso and the chiral dl forms. The meso isomer is used as chelating agent.
Additional recommended knowledge
Meso 2,3-dimecaptosuccinic acid is used to sequester heavy metals such as mercury and lead for excretion. DMSA can cross the blood-brain barrier, and thus is useful for extracting heavy metals from the brain.
DMSA is also called succimer and is sold under the brand name Chemet®. The dimethylester is also known.
Categories: Dicarboxylic acids | Thiols | Chelating agents
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dimercaptosuccinic_acid". A list of authors is available in Wikipedia.|