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Disopyramide



Disopyramide
Systematic (IUPAC) name
4-dipropan-2-ylamino-2-phenyl-2-pyridin-2-yl-butanamide
Identifiers
CAS number 3737-09-5
ATC code C01BA03
PubChem 3114
DrugBank APRD00507
Chemical data
Formula C21H29N3O 
Mol. mass 339.475 g/mol
Pharmacokinetic data
Bioavailability High
Protein binding 50% to 65%
(concentration-dependent)
Metabolism Hepatic (CYP3A4-mediated)
Half life 6.7 hours (range 4 to 10 hours)
Excretion Renal (80%)
Therapeutic considerations
Pregnancy cat.

B2(AU) C(US)

Legal status

POM(UK) -only(US)

Routes Oral, intravenous

Disopyramide (INN, trade names Norpace® and Rythmodan®) is an antiarrhythmic medication. It is a Class Ia antiarrythmic used in the treatment of ventricular tachycardias. It has no effect on alpha or beta adrenergic receptors.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Disopyramide". A list of authors is available in Wikipedia.
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