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Ajmaline


Ajmaline
Systematic (IUPAC) name
?
Identifiers
CAS number	4360-12-7
ATC code	C01BA05
PubChem	20367
Chemical data
Formula	C₂₀H₂₆N₂O₂
Mol. mass	326.433 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Ajmaline is a class Ia antiarrhythmic agent. It is often used to Bring out typical findings of ST elevations in patients suspected of having Brugada syndrome.

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The compound was first isolated by Salimuzzaman Siddiqui in 1931 ^[1] from the roots of Rauwolfia serpentina. He named it Ajmaline, after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani system of medicine in South Asia.^[2]

Notes

^ Siddiqui, S. & Siddiqui, R.H. (1931). Journal of the Indian Chemical Society, vol. 8, pp. 667-680.
^ Ahmed Nasim Sandilvi (2003), Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan. Daily Dawn. 12 April, 2003. Retrieved on 19 July 2007.

v • d • e Antiarrhythmic agents (C01B)
class Ia	Ajmaline • Disopyramide • Prajmaline • Procainamide • Quinidine • Sparteine
class Ib	Aprindine • Lidocaine • Mexiletine • Tocainide
class Ic	Encainide • Flecainide • Lorcainide • Moricizine • Propafenone
class II	Propranolol • Metoprolol • Nadolol • Atenolol • Acebutolol • Pindolol see Beta blockers (C07)
class III	Amiodarone • Bretylium tosylate • Bunaftine • Dofetilide • Ibutilide • Sotalol
class IV	Verapamil • Diltiazem see Calcium channel blockers (C08)
class V	Adenosine • Atropine • Digoxin