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Additional recommended knowledge
All reactions of gramine follow the same general reaction scheme. Gramine is reacted with a strong electrophile, such as methyl iodide, to form the quaternary ammonium salt 2. The ammonium salt will undergo a Hofmann elimination or retro-Michael addition to give the very active intermediate 3, which can accept a wide range of nucleophiles to give the desired product 4.
Gramine has been found in the ArundoPhalaris plant species., silver maple , Hordeum, and
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gramine". A list of authors is available in Wikipedia.|