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Hemetsberger indole synthesis
The Hemetsberger indole synthesis (also called the Hemetsberger-Knittel synthesis) is a chemical reaction that thermally decomposes a 3-aryl-2-azido-propenoic ester into an indole-2-carboxylic ester.
Additional recommended knowledge
Yields are typically above 70%. However, this is not a popular reaction, due to the lack of stability and difficulty in synthesizing the starting material.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hemetsberger_indole_synthesis". A list of authors is available in Wikipedia.|