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Her 4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Symbol ERBB4
Entrez 2066
HUGO 3432
OMIM 600543
RefSeq NM_001042599
UniProt Q15303
Other data
Locus Chr. 2 q34

Her-4, more commonly called ErbB4, is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. Like the epidermal growth factor receptor, Her-4 is able to bind to several activating ligands and dimerize with every other member of the EGFR family. Knock-outs of Her-4 in mice show developmental defects. However, Her-4 is thought to be expressed in low quantities, if at all, in most tissues, in contrast to the other Her receptors.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Her_4". A list of authors is available in Wikipedia.
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