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IUPAC name 3-Aminopropane-1-sulfonic acid
Other names Tramiprosate
CAS number 3687-18-1
PubChem 1646
Molecular formula C3H9NO3S
Molar mass 139.17346
Melting point

293 °C (decomposition)

R-phrases R36/37/38
S-phrases S26 S36
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Homotaurine (also spelled homotaurin) is a synthetic organic compound. It is analogous to taurine, but with an extra carbon in its chain. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAnergic effects and may be useful as an anticonvulsant.[2]

Homotaurine is also being investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain.[3]


  1. ^ Homotaurine at Sigma-Aldrich
  2. ^ Fariello RG, Golden GT, Pisa M (1982). "Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid". Neurology 32 (3): 241–5. PMID 7199633.
  3. ^ Aisen PS, Gauthier S, Vellas B, et al (2007). "Alzhemed: a potential treatment for Alzheimer's disease". Curr Alzheimer Res 4 (4): 473–8. PMID 17908052.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Homotaurine". A list of authors is available in Wikipedia.
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