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Levonantradol



Levonantradol
Systematic (IUPAC) name
[(6S,6aR,9R,10aR)-9-hydroxy-6-methyl-3-[(2R)-5-phenylpentan-2-yl] oxy-5,6,6a,7,8,9,10,10a-octahydrophenanthridin-1-yl] acetate
Identifiers
CAS number 71048-87-8
ATC code  ?
PubChem 5361881
Chemical data
Formula C27H35NO4 
Mol. mass 437.571 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Levonantradol (Nantrodolum) is a synthetic cannabinoid analog of dronabinol (Marinol). It exhibits antiemetic and analgesic effects, most likely by binding to and activating CB1 and CB2 cannabinoid receptors. Levonantradol is not currently used in medicine as dronabinol or nabilone are felt to be more useful for most conditions, however it is widely used in research into the potential therapeutic applications of cannabinoids. [1] [2] [3]

Additional recommended knowledge



References

  1. ^ Tramer MR, Carroll D, Campbell FA, Reynolds DJ, Moore RA, McQuay HJ. Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review. British Medical Journal 2001 Jul 7;323(7303):16-21.
  2. ^ Campbell FA, Tramer MR, Carroll D, Reynolds DJ, Moore RA, McQuay HJ. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. British Medical Journal. 2001 Jul 7;323(7303):13-6.
  3. ^ Ben Amar M. Cannabinoids in medicine: A review of their therapeutic potential. Journal of Ethnopharmacology. 2006 Apr 21;105(1-2):1-25.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Levonantradol". A list of authors is available in Wikipedia.
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