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JWH-133 is a potent selective CB2 receptor agonist.
Additional recommended knowledge
JWH-133, along side WIN 55,212-2 and HU-210, is implicated in preventing the inflammation caused by Amyloid beta proteins involved in Alzheimer's Disease, in addition to preventing cognitive impairment and loss of neuronal markers. This antiinflmatory action is induced through the agonization of cannabinoid receptors which prevents microglial activation that elicits the inflammation. Additionally, cannabinoids completely abolish neurotoxicity related to microglia activation in rat models.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "JWH-133". A list of authors is available in Wikipedia.|