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The M1 protein is a matrix protein of the influenza virus. It forms a coat inside the viral envelope.
Additional recommended knowledge
It also has multiple regulatory functions, performed by interaction with the components of the host cell. The mechanisms regulated include the export of the viral ribonucleoproteins from the host cell nucleus, inhibition of viral transcription, and plays a role in the virus assembly and budding. The protein was found to undergo phosphorylation in the host cell.
The M1 protein forms a layer under the patches of host cell membrane that are rich with the viral hemagglutinin, neuraminidase and M2 transmembrane proteins, and facilitates budding of the mature viruses.
Sources and notes
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "M1_protein". A list of authors is available in Wikipedia.|