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Systematic (IUPAC) name
CAS number 114-86-3
ATC code A10BA01
PubChem 8249
DrugBank APRD00511
Chemical data
Formula C10H15N5 
Mol. mass 205.26 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Phenformin is an anti-diabetic drug from the biguanide class. It is no longer widely available because it is known to induce lactic acidosis.[1]

Like metformin, phenformin leads to weight loss, something often desirable in type 2 diabetics, and it is for this reason that there is still some interest in it.[2]


  1. ^ Enia G, Garozzo M, Zoccali C (1997). "Lactic acidosis induced by phenformin is still a public health problem in Italy.". BMJ 315 (7120): 1466-7. PMID 9418116.
  2. ^ Rosand J, Friedberg J, Yang J (1997). "Fatal phenformin-associated lactic acidosis.". Ann Intern Med 127 (2): 170. PMID 9230023.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phenformin". A list of authors is available in Wikipedia.
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