Phenformin is an anti-diabetic drug from the biguanide class. It is no longer widely available because it is known to induce lactic acidosis.
Additional recommended knowledge
Like metformin, phenformin leads to weight loss, something often desirable in type 2 diabetics, and it is for this reason that there is still some interest in it.
- ^ Enia G, Garozzo M, Zoccali C (1997). "Lactic acidosis induced by phenformin is still a public health problem in Italy.". BMJ 315 (7120): 1466-7. PMID 9418116.
- ^ Rosand J, Friedberg J, Yang J (1997). "Fatal phenformin-associated lactic acidosis.". Ann Intern Med 127 (2): 170. PMID 9230023.
|Oral antidiabetic drugs and Insulin analogs (A10)|
|Sulfonylureas||Chlorpropamide, Glibenclamide (Glyburide), Gliclazide, Glimepiride, Glipizide, Gliquidone, Tolazamide, Tolbutamide|
|Alpha-glucosidase inhibitors||Acarbose, Miglitol, Voglibose|
|Thiazolidinediones (TZD)||Pioglitazone, Rosiglitazone, Troglitazone|
|Meglitinides||Nateglinide, Repaglinide, Mitiglinide|
|Dipeptidyl peptidase-4 (DPP-4) inhibitors||Saxagliptin, Sitagliptin, Vildagliptin|
|Glucagon-like peptide-1 analog||Exenatide|
|Insulin analogs||fast acting (Insulin lispro, Insulin aspart, Insulin glulisine), intermediate-acting (NPH insulin), long acting (Insulin glargine, Insulin detemir)|