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Wilhelm Rudolph Fittig

  Wilhelm Rudolph Fittig (b. December 6, 1835, Hamburg, Germany – November 19, 1910) was a German chemist. Fittig was responsible for discovery of the pinacol coupling reaction, mesitylene, diacetyl and biphenyl. He studied the action of sodium on ketones and hydrocarbons. He discovered the Fittig reaction or Wurtz-Fittig reaction for the synthesis of alkylbenzenes, he proposed a diketone structure for benzoquinone and isolated phenanthrene from coal tar. He discovered and synthesized the first lactones and investigated structures of piperine naphthalene and fluorene.


Fittig studied chemistry at Göttingen, graduating as Ph.D. with a dissertation on acetone in 1858, under the supervision of Heinrich Limpricht and Friedrich Wöhler. He subsequently held several appointments at Göttingen, being privat dozent (1860), and extraordinary professor (1870). In 1870 he obtained the chair at Tübingen, and in 1876 that at Strassburg, where the laboratories were erected from his designs. Fittig's researches are entirely in organic chemistry, and cover an exceptionally wide field. The aldehydes and ketones provided material for his earlier work. He observed that aldehydes and ketones may suffer reduction in neutral, alkaline, and sometimes acid solution to secondary and tertiary glycols, substances which he named pinacones; and also that certain pinacones when distilled with dilute sulphuric acid gave compounds, which he named pinacolines. The unsaturated acids also received much attention, and he discovered the internal anhydrides of oxyacids, termed lactones. In 1863 he introduced the reaction known by his name. In 1855 Adolph Wurtz had shown that when sodium acted upon alkyl iodides, the alkyl residues combined to form more complex hydrocarbons; Fittig developed this method by showing that a mixture of an aromatic and alkyl haloid, under similar treatment, yielded homologues of benzene. His investigations on Perkins reaction led him to an explanation of its mechanism which appeared to be more in accordance with the facts. The question, however, is one of much difficulty, and the exact course of the reaction appears to await solution. These researches incidentally solved the constitution of coumarin, the odoriferous principle of woodruff. Fittig and Erdmann's observation that phenyl isocrotonic acid readily yielded α-naphthol by loss of water was of much importance, since it afforded valuable evidence as to the constitution of raphthalene. They also investigated certain hydrocarbons occurring in the high boiling point fraction of the coal tar distillate and solved the constitution of phenanthrene. We also owe much of our knowledge of the alkaloid piperine to Fittig, who in collaboration with Ira Remsen established its constitution in 1871. Fittig has published two widely used textbooks; be edited several editions of Wohler's Grundriss der organischen Chemie (11th ed., 1887) and wrote an Unorganische Chemie (1st ed., 1872; 3rd, 1882). His researches have been recognized by many scientific societies and institutions, the Royal Society awarding him the Davy medal in 1906.


  • This article incorporates text from the Encyclopædia Britannica Eleventh Edition, a publication now in the public domain.
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