New methods for reliable evaluation of chemicals and pharmaceuticals

18 partners from eight countries are working on the introduction of innovative methods for evaluating safety and efficacy without animal testing

24-Feb-2025 - BioRegio STERN Management GmbH is a German partner in the European NAMWISE (New Approach Methodologies Within Integrated Safety & Efficacy evaluation of chemicals and pharmaceuticals) project, which is coordinated by the French Institut National de l’Environment Industriel et des Risques – ...

Using metabolomics for assessing safety of chemicals may reduce the use of lab rats

"We hope that learnings from this research will be included in new guidance for the chemical industry to allow commercial laboratories to provide these services widely"

26-Feb-2024 - Scientists have discovered a more robust way of grouping chemicals and using read-across for toxicological data to meet regulatory requirements, which could greatly reduce animal testing. The safety of chemicals is taken incredibly seriously by regulators and as such industry must meet certain ...

BASF to research on alternatives to animal testing on behalf of the European Chemicals Agency

Number of animal experiments required for safety assessments of chemical substances to be further reduced

07-Feb-2024 - The European Chemicals Agency (ECHA) has contracted a consortium that includes BASF to conduct scientific studies on the reliability and relevance of New Approach Methodologies (NAMs) as alternatives to animal testing and to promote the use of such methods in the future. The aim of the contract ...

Where do toxins from tobacco attack DNA?

In the future, this could make it easier than ever to determine the safety of many chemical substances

24-Feb-2023 - It is known that toxins in tobacco smoke can change our DNA – but where exactly in the genome they do this has been a mystery. A new approach developed by researchers at ETH Zurich now brings light into the darkness. In the future, this could make it easier than ever to determine the safety of ...

New EU Regulation for export and import of hazardous chemicals enters into operation

04-Mar-2014 - PIC regulates the import and export of very hazardous chemicals between the European Union and third countries, and implements the global Rotterdam Convention within the EU. Export of these chemicals cannot take place until the receiving country has been informed. In some cases, an ‘explicit ...

REACH Evaluation Report 2013

Results and recommendations from dossier evaluation

27-Feb-2014 - The annual evaluation report covers the Agency's evaluation activities and the corresponding output. In 2013, the focus of dossier evaluation activities was on compliance checks: 928 checks were concluded during the year. Altogether, ECHA has checked 1 130 dossiers, thereby exceeding the 5 % ...

Target met for 5% compliance checks of the 2010 registration dossiers

16-Jan-2014 - By 1 December 2010, the industry registered the substances manufactured or imported in quantities of more than 1 000 tonnes per year and also the most hazardous substances (carcinogenic, mutagenic, toxic to reproduction; persistent, bioaccumulative, toxic and very persistent and very ...

New tests for determining health and environmental effects of nanomaterials

23-Aug-2013 - A group of international experts from government, industry and academia have concluded that alternative testing strategies (ATSs) that don't rely on animals will be needed to cope with the wave of new nanomaterials emerging from the boom in nanoscience and nanotechnology. Their consensus ...

ECHA and stakeholders set out actions to improve chemical safety reports and safety data sheets

22-Jul-2013 - ECHA publishes today a roadmap towards enhancing the quality of information communicated in the exposure scenarios included in the REACH chemical safety reports and in the extended safety data sheets. These documents hold essential information on the safe use of chemical substances and mixtures ...

EU Court confirms ECHA PBT assessment of substances

12-Mar-2013 - ECHA welcomes the EU General Court's conclusions which confirm the Agency's approach in identifying PBTs and vPvBs as substances of very high concern. The ruling confirms that ECHA's approach in identifying UVCB[1] substances as well as other multi-constituent substances as PBTs[2] or vPvBs[3] on ...