XtaLAB Synergy-ED

• Easy-to-use, designed for crystallographers – no microscopy experience needed.
• Directly determine 3D molecular structures of submicron crystals.
• Full integration of instrument control, sample screening, data collection, and data processing in Rigaku’s powerful single-crystal analysis software CrysAlis^Pro.
• Rigaku’s single-electron-sensitive, background-free detector HyPix-ED.
• JEOL’s expertise in generation and control of stable electron beams – 200 kV electron source and electron optics, including zoom system for adjustable virtual detector distance.
• Many sample environments are available, including cryo-transfer, heating, and gas cell.

The XtaLAB Synergy-ED is the world’s first dedicated diffractometer for 3D ED/MicroED and the successful culmination of a joint development project between Rigaku and JEOL. 3D ED/MicroED allows crystallographers to probe the structure of crystals as small as tens of nanometers, opening up many new possibilities beyond the limitations of single-crystal X-ray diffraction (SC-XRD), which typically requires samples greater than 1 µm. With 3D ED/MicroED many more samples become viable targets for structural research. Challenging structures that previously required combination of multiple techniques and therefore significant periods of time to assemble evidence of the structure can now be elucidated within minutes.

The compact design of the XtaLAB Synergy-ED allows it to be located in laboratories alongside SC-XRD instruments, adding an excellent complimentary technique to every crystallographic facility. Crystallographers familiar with Rigaku diffractometers running CrysAlis^Pro will be able to adapt to the instrument very quickly, as it is based on the same intuitive platform. The fully integrated system incorporates a seamless workflow from data collection to structure determination of three-dimensional molecular structures. AutoChem, which is fully integrated into CrysAlis^Pro, performs fast, fully automated structure solution and refinement during data collection, optimizing your productivity.