Alliance iS™

The combined power of the Waters Alliance iS HPLC System, Alliance iS Bio HPLC System, and Empower Chromatography Data System (CDS) delivers a unified, compliance‑ready workflow designed to help modern QC and biopharmaceutical laboratories operate with greater accuracy, efficiency, and confidence.

Built for the escalating demands of regulated environments, the Alliance iS HPLC System introduces intuitive simplicity and system intelligence that reduces human error by up to 40%, enhances productivity, and maximizes uptime through guided operations and performance safeguards. Its touchscreen interface and error‑prevention tools support consistent system preparation, enabling QC teams to achieve first‑time‑right results and shorter release cycles.

For biologics and metal‑sensitive analytes, the Alliance iS Bio HPLC System extends this capability with MaxPeak High Performance Surfaces (HPS) Technology, delivering exceptionally bio‑inert separations that minimize analyte loss, improve reproducibility, and increase sensitivity. Purpose‑built for biopharma QC, it reduces unwanted analyte interactions, minimizes non‑specific adsorption of compounds such as oligonucleotides and phosphopeptides, and eliminates lengthy conditioning steps. The result is faster, more reliable bioseparations with higher data integrity and reduced training requirements thanks to intuitive touchscreen workflows.

Completing the solution, Empower Software provides the industry’s leading chromatography data management environment—centralizing acquisition, processing, reporting, and audit‑ready compliance controls. It ensures traceability, secure data integrity, and seamless instrument integration, enabling labs to work more efficiently while meeting global regulatory expectations. When paired with the Alliance iS and Alliance iS Bio HPLC Systems, Empower Software creates a fully connected analytical workflow with intelligent method guidance, automated system checks, and consistent, scalable data management across instruments and sites.

Together, these three technologies form a robust, end‑to‑end solution for QC and biopharma laboratories seeking higher throughput, reduced error rates, improved method consistency, and complete confidence in their data. With advanced bio‑inert performance, built‑in system intelligence, and enterprise‑ready informatics, Waters delivers the modern platform you can depend on to accelerate scientific output while safeguarding quality at every step.