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Acetohexamide



Acetohexamide
Systematic (IUPAC) name
1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea
Identifiers
CAS number 968-81-0
ATC code A10BB31
PubChem 1989
DrugBank APRD00773
Chemical data
Formula C15H20N2O4S 
Mol. mass 324.396 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 90%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Acetohexamide (Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.

Additional recommended knowledge

Mechanism of Action

Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Risks

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition [1].


References

  1. a  Medline Plus - Acetohexamide


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Acetohexamide". A list of authors is available in Wikipedia.
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