My watch list
my.chemeurope.com  
Login  

Almotriptan



Almotriptan
Systematic (IUPAC) name
N,N-dimethyl-2- [5-(pyrrolidin-1-ylsulfonylmethyl)- 1H-indol-3-yl]-ethanamine
Identifiers
CAS number 154323-57-6
ATC code N02CC05
PubChem 123606
DrugBank APRD00169
Chemical data
Formula C17H25N3O2S 
Mol. mass 335.465 g/mol
Pharmacokinetic data
Bioavailability 70%
Protein binding 35%
Metabolism  ?
Half life 3-4 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C(USA)

Legal status

Prescription only

Routes Oral

Almotriptan (Axert®, Almogran®) is a triptan drug discovered by Almirall Prodesfarma and licensed to Ortho-McNeil for the treatment of migraine headaches. It is available in strengths of 6.25 and 12.5 mg as a tablet.

Additional recommended knowledge

In the United States and Canada almotriptan is available under the name Axert® only by prescription. AXERT® for oral administration contains almotriptan malate equivalent to 6.25 or 12.5 mg of almotriptan. Each compressed tablet contains the following inactive ingredients: mannitol, cellulose, povidone, sodium starch glycolate, sodium stearyl fumarate, titanium dioxide, hypromellose, polyethylene glycol, propylene glycol, iron oxide (6.25 mg only), FD&C Blue No. 2 (12.5 mg only), and carnauba wax. The brand Almogran is used in Belgium, Finland, France, Germany, Italy, Portugal, Spain and the United Kingdom. Each 12.5 mg. tablet contains the following inactiva ingredients: carnauba wax, hypromellose, indigo carmine (E132), macrogol 400, mannitol, microcrystalline cellulose, povidone, propylene glycol, sodium starch glycollate, sodium stearyl fumarate and titanium dioxide (E171).


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Almotriptan". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE