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See also: Colony Collapse Disorder
IUPAC name S-(3,4-Dihydro-4-oxobenzo[d]-
O,O-dimethyl phosphorodithioate
Other names Azinphos-methyl
CAS number 86-50-0
RTECS number TE1925000
Molecular formula C10H12N3O3PS2
Molar mass 317.32 g mol−1
Appearance Brown, waxy solid
Density 1.44 g cm−3, solid
Melting point

73 °C (346 K)

Boiling point

>200 °C (decomp.)

Solubility in water 28 mg/L
MSDS External MSDS
Main hazards highly toxic
NFPA 704
R-phrases R24 R28
S-phrases S28 S36 S37 S45
Flash point 69 °C
Related Compounds
Related organophosphates malathion
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Azinphos-methyl (Guthion) is a broad spectrum organophosphate insecticide manufactured by Bayer CropScience, Gowan Co., and Makhteshim Agan.[1] Like other pesticides in this class, it owes its insecticidal properties (and human toxicity) to the fact that it is an acetylcholinesterase inhibitor.

History and Uses

Azinphos-methyl is a dangerous neurotoxin derived from nerve agents developed during World War II. In the US, it is registered for use on select nut trees, vegetable crops, and fruit trees. It is not registered for consumer or residential use. It has been linked to health problems of farmers who apply it, and the U.S. Environmental Protection Agency (EPA) considered a denial of reregistration, citing, “concern to farm workers, pesticide applicators, and aquatic ecosystems."[2] After settling a 2004 lawsuit brought by the United Farm Workers of America and other groups, the EPA accounced it would begin phasing out the remaining uses of the pesticide in 2007 with all uses ending in 2012. In January 2007, the suit was reopened, with the plaintiffs seeking a quicker phaseout.[3]


  1. ^ EPA's Interrum Reregistration Eligibility Decesion for Azinphos-methyl
  2. ^ ibid.
  3. ^ Earthjustice press release announcing the reopening of the azinphos-methyl lawsuit.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Azinphos-methyl". A list of authors is available in Wikipedia.
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