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Bis(trimethylsilyl)amine (also known as hexamethyldisilazane, or HMDS) a chemical reagent with molecular formula (CH3)3Si-NH-Si(CH3)3 which consists of ammonia substituted with two trimethylsilyl functional groups. It is a clear, colorless liquid that will hydrolize slowly upon exposure to water.
A bis(trimethylsilyl)amide (also known as hexamethyldisilazide) results from the deprotonation of the nitrogen atom of bis(trimethylsilyl)amines and are used as non-nucleophilic bases:
Examples of these bases are:
Additional recommended knowledge
Uses in organic chemistry
One of the uses of HMDS is as a reagent in condensation reactions of heterocyclic compounds such as in the microwave synthesis of a derivative of xanthine:
HMDS is often used in Photolithography as an adhesion promoter for Photoresist. Best results are obtained by applying HMDS from the gas phase on heated substrates.
Categories: Amines | Organosilicon compounds | Reagents for organic chemistry
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bis(trimethylsilyl)amine". A list of authors is available in Wikipedia.|