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Calcium-activated potassium channel
This family of ion channels is, for the most part, activated by intracellular Ca2+ and contains 8 members. It should be noted, however, that some of these channels (the KCa4 and KCa5 channels) are responsive instead to intracellular Na+ and Cl-. Furthermore, the KCa1 family is both Ca2+ and voltage activated, further complicating the description of this family. The KCa channel α subunits have six transmembrane segments similar to the KVs, except KCa1, in which the N-terminus makes a seventh pass across the membrane to end up outside the cell. The α subunits make homo- and hetero-tetrameric complexes.
Additional recommended knowledge
Below is a list of the 8 known calcium-activated potassium channel grouped according to sequence homology of transmembrane hydrophobic cores:
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Calcium-activated_potassium_channel". A list of authors is available in Wikipedia.|