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N-type calcium channel
The N-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.
Additional recommended knowledge
N-type ('N' for "Neural-Type") calcium channels are found primarily at presynaptic terminals and are involved in neurotransmitter release. Strong depolarization by an action potential causes these channels to open and allow influx of Ca2+, initiating vesicle fusion and release of stored neurotransmitter. N-type channels are blocked by ω-conotoxin.
The analgesic drug ziconotide inhibits N-type channels.
Categories: Ion channels | Electrophysiology | Integral membrane proteins
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "N-type_calcium_channel". A list of authors is available in Wikipedia.|