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Cholic acid

Cholic acid
IUPAC name 3α,7α,12α-trihydroxy-5β-cholanic acid
CAS number 81-25-4
SMILES C[C@@]34[C@] (CC[C@@H]4[C@@H]
(CCC(O)=O)C) ([H])[C@]2([H]) [C@H](O)C[C@]1
([H])C[C@H](O) CC[C@@](C)1[C@] ([H])2C[C@@H]3O
Molecular formula C24H40O5
Molar mass 408.57 g/mol
Melting point

200-201 °C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Cholic acid is a bile acid, a white crystalline substance insoluble in water (soluble in alcohol and acetic acid), with a melting point of 200-201 °C. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of two major bile acids produced by the liver where it is synthesized from cholesterol. Of the two major bile acids, cholate derivatives represent approximately eighty percent of all bile acids. These derivatives are made from cholyl-CoA which forms a conjugate with either glycine, or taurine, yielding glycocholic and taurocholic acid respectively.

Cholic acid and chenodeoxycholic acid are the most important human bile acids. Some other mammals synthesize predominantly deoxycholic acid.


    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cholic_acid". A list of authors is available in Wikipedia.
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