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Flavones are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one) shown on the right.
Additional recommended knowledge
In organic chemistry several methods exist for the synthesis of flavones:
Another method is the dehydrative cyclization of certain 1,3-diaryl diketones 
The Wessely-Moser rearrangement (1930)  has been an important tool in structure elucidation of flavonoids. It involves the conversion of 5,7,8-trimethoxyflavone into 5,6,7-trihydroxyflavone on hydrolysis of the methoxy groups to phenol groups. It also has synthetic potential for example:
This rearrangement reaction takes place in several steps: A ring opening to the diketone, B bond rotation with formation of a favorable acetylacetone-like phenyl-ketone interaction and C hydrolysis of two methoxy groups and ring closure.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Flavones". A list of authors is available in Wikipedia.