My watch list
my.chemeurope.com  

my.chemeurope.com

With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

GDP-fucose protein O-fucosyltransferase 2




protein O-fucosyltransferase 2
Identifiers
Symbol POFUT2
Alt. Symbols C21orf80
Entrez 23275
HUGO 14683
OMIM 610249
RefSeq NM_133634
UniProt Q9Y2G5
Other data
Locus Chr. 21 q22.3

Additional recommended knowledge

Recognize and detect the effects of electrostatic charges on your balance

What is the Correct Way to Check Repeatability in Balances?

How to ensure accurate weighing results every day?

GDP-fucose protein O-fucosyltransferase 2 (POFUT2) is an enzyme responsible for adding fucose sugars in O linkage to serine or threonine residues in Thrombospondin repeats. The protein is an inverting glycosyltransferase, which means that the enzyme uses GDP-β-L-fucose as a donor substrate and transfers the fucose in O linkage to the protein producing fucose-α-O-serine/threonine.

Almost all glycosyltransferases reside in the Golgi apparatus. However, POFUT2 as well as the related enzyme POFUT1 have recently been shown to reside in the endoplasmic reticulum.

v • d • e
Transferases: glycosyltransferases (EC 2.4)
2.4.1 - Hexosyltransferases:
glucosyltransferase		Phosphorylase (Starch, Glycogen, Myo-) - Glycogen synthase - Debranching enzyme - Branching enzyme - 1,3-beta-glucan synthase - Ceramide glucosyltransferase
2.4.1 - Hexosyltransferases:
other		Galactosyltransferase (Lactose synthase, B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase) - Glucuronosyltransferase (UGT1A1, UGT2B7, Hyaluronan synthase) - Fucosyltransferase (POFUT1, POFUT2)
2.4.2 - Pentosyltransferases:
ADP ribose		Cholera toxin - Diphtheria toxin - Pertussis toxin - Poly ADP ribose polymerase
2.4.2 - Pentosyltransferases:
other		Purine nucleoside phosphorylase - Adenine phosphoribosyltransferase - Hypoxanthine-guanine phosphoribosyltransferase - Uracil phosphoribosyltransferase - Amidophosphoribosyltransferase
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "GDP-fucose_protein_O-fucosyltransferase_2". A list of authors is available in Wikipedia.
Topics A-Z
All topics
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE