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Lercanidipine


Lercanidipine
Systematic (IUPAC) name
methyl[2-(3,3-diphenylpropyl-methyl-amino)- 1,1-dimethyl-ethyl] 2,6-dimethyl- 4-(3-nitrophenyl)- 1,4-dihydropyridine-3, 5-dicarboxylate
Identifiers
CAS number	100427-26-7
ATC code	C08CA13
PubChem	65866
DrugBank	APRD00193
Chemical data
Formula	C₃₆H₄₁N₃O₆
Mol. mass	611.727 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Lercanidipine is a calcium channel blocker of the dihydropyridine class.

It is sold under various commercial names including Zanidip.

Lin T, Voon W, Yen H, Huang C, Su H, Lai W, Sheu S (2006). "Lercanidipine and losartan effects on blood pressure and fibrinolytic parameters.". Kaohsiung J Med Sci 22 (4): 177-83. PMID 16679299.
Martinez M, Lopes L, Coelho E, Nobre F, Rocha J, Gerlach R, Tanus-Santos J (2006). "Lercanidipine reduces matrix metalloproteinase-9 activity in patients with hypertension.". J Cardiovasc Pharmacol 47 (1): 117-22. PMID 16424795.
Agrawal R, Marx A, Haller H (2006). "Efficacy and safety of lercanidipine versus hydrochlorothiazide as add-on to enalapril in diabetic populations with uncontrolled hypertension.". J Hypertens 24 (1): 185-92. PMID 16331117.

v • d • e Calcium channel blockers (C08)
Dihydropyridines	Amlodipine • Felodipine • Isradipine • Lacidipine • Lercanidipine • Nicardipine • Nifedipine • Nimodipine • Nisoldipine • Nitrendipine
Phenylalkylamines	Verapamil
Benzothiazepines	Diltiazem