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Ofloxacin


Ofloxacin
Systematic (IUPAC) name
(+/-)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)- 7-oxo-7H-pyrido [1,2,3-de]-1, 4-benzoxazine-6-carboxylic acid
Identifiers
CAS number	82419-36-1
ATC code	J01MA01 J01MA02, J01MA12, S01AX11, S01AX13, S01AX19, S03AA07
PubChem	4583
DrugBank	APRD00502
Chemical data
Formula	C₁₈H₂₀F N₃O₄
Mol. mass	361.368 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	32%
Metabolism	?
Half life	9 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	C(US)
Legal status	℞-only(US)
Routes	Topical (ear drops)

Ofloxacin (sold under the brand name Floxin® in the United States, Tarivid® in Europe and some other countries) is a fluoroquinolone antibiotic. Ofloxacin is the racemic mixture of the chiral compound. The biologically active enantiomer is sold separately under the name of levofloxacin. It is used as a treatment for gonorrhoea and is an alternative treatment to ciprofloxacin for anthrax.

v • d • e Antibacterials for systemic use: quinolones (J01M)
Fluoroquinolones	Ciprofloxacin • Enoxacin • Fleroxacin • Gatifloxacin • Gemifloxacin • Grepafloxacin • Levofloxacin • Lomefloxacin • Moxifloxacin • Norfloxacin • Ofloxacin • Pefloxacin • Prulifloxacin • Rufloxacin • Sparfloxacin • Temafloxacin • Trovafloxacin • Sitafloxacin
Other quinolones	Cinoxacin • Flumequine • Nalidixic acid • Oxolinic acid • Pipemidic acid • Piromidic acid • Rosoxacin