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Protein ligands



In biochemistry, a protein ligand is an atom, a molecule or an ion which can bind to a specific site (the binding site) on a protein. Interactions between any protein and its ligands are fundamental and essential for the protein to function properly.

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Main methods to study protein-ligand interactions are principal hydrodynamic and calorimetric techniques, and principal spectroscopic and structural methods such as

The dramatically increased computing power of supercomputers and personal computers has made it possible to study protein-ligand interactions also by means of computational chemistry. For example, a worldwide grid of well over a million ordinary PCs was harnessed for cancer research in the project grid.org, which ended in April 2007. Grid.org has been succeeded by similar projects such as World Community Grid, Human Proteome Folding Project, Compute Against Cancer and Folding@Home.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Protein_ligands". A list of authors is available in Wikipedia.
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